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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG1 All Species: 23.64
Human Site: T123 Identified Species: 47.27
UniProt: P18858 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18858 NP_000225.1 919 101736 T123 S G I P K R R T A R K Q L P K
Chimpanzee Pan troglodytes XP_524321 919 101662 T123 S G I P K G R T A R K Q L P K
Rhesus Macaque Macaca mulatta XP_001111346 919 101454 T123 S G I P K R R T A R K Q L P K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P37913 916 102271 T123 S G F P K R R T A R K Q L P K
Rat Rattus norvegicus Q9JHY8 918 102463 T124 S G F P K R R T A R K Q L P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P51892 1070 120215 Q130 S A R K E T P Q S A R K E T P
Zebra Danio Brachydanio rerio NP_001119860 1058 118776 T151 S G I P K R K T A R K Q F P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1H4 747 84700 S20 S D A T D S P S P P K K V P K
Honey Bee Apis mellifera XP_392286 861 97795 I119 K K T N T K K I L K D T I N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180844 967 108403 K147 K K D V P L R K T A R K H M R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42572 790 87722 A63 F D A L M S N A R A A A K K K
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 L28 P L L M S S S L P S S A G K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 98.2 N.A. N.A. 84 81.3 N.A. N.A. N.A. 56.9 56.1 N.A. 44 46 N.A. 48.5
Protein Similarity: 100 99.4 98.8 N.A. N.A. 89.3 87.8 N.A. N.A. N.A. 71.1 68.6 N.A. 60.2 65.7 N.A. 66.2
P-Site Identity: 100 93.3 100 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. 6.6 86.6 N.A. 26.6 0 N.A. 6.6
P-Site Similarity: 100 93.3 100 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. 33.3 93.3 N.A. 46.6 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 40.3 36 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 0 0 0 9 50 25 9 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 9 0 9 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 9 0 17 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 50 0 0 0 9 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 34 0 0 0 0 9 0 0 0 0 9 0 0 % I
% Lys: 17 17 0 9 50 9 17 9 0 9 59 25 9 17 75 % K
% Leu: 0 9 9 9 0 9 0 9 9 0 0 0 42 0 9 % L
% Met: 0 0 0 9 9 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 9 0 0 9 0 0 0 0 0 0 9 0 % N
% Pro: 9 0 0 50 9 0 17 0 17 9 0 0 0 59 9 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 50 0 0 0 % Q
% Arg: 0 0 9 0 0 42 50 0 9 50 17 0 0 0 9 % R
% Ser: 67 0 0 0 9 25 9 9 9 9 9 0 0 0 0 % S
% Thr: 0 0 9 9 9 9 0 50 9 0 0 9 0 9 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _